Co-organized with Sam Hege, this roundtable seeks to explore not only how the logics of exposure have become an integral component of environmental knowledge; by involving experts on the Mississippi Delta region, it also aims to activate conversation about how communities and social actors, past and present, have understood, withstood, or countered the material distributions and legacies of exposure within the environs surrounding this year’s HSS meeting. In doing so, it embodies a relational sensibility attentive to the complex entanglement of material vectors, elemental forces, and systems of multiple kinds. Participants will address how the knowledge and action of ecosystems, bureaucratic regulatory regimes, plantation economies, petrochemical infrastructures, medical understandings of health and climate, the logics of historical preservation, and modes of collective memory-making intersect with the deep histories of political and social stratification that characterize the region. Rather than positing natural processes or social structures as a priori determinants in ecologies of exposure, panelists will share how they combine various methods, such as ethnographic narrative, material analysis, GIS mapping techniques, and archival research, in order to unearth how more-than-human agencies become intertwined with anthropocentric legacies within materializations of exposure. Through this locally-grounded focus, our roundtable discussion will bring experts on the region from multiple disciplines into conversation with fellow colleagues visiting New Orleans to sketch out new trajectories, theories, and methods for understanding how both social histories and histories of science shape, and are shaped by, emergent as well as enduring ecologies of exposure. Roundtable Presenters include : Shannon Lee Dawdy, University of Chicago; Kathryn Olivarius, Stanford University; Ashley Rogers, Whitney Plantation; Leila Blackbird, University of Chicago